fumaric acid pka

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification. Furthermore, updates in the source data may not always result in an update of the Brief Profile. Log Pow (Log Kow) provides substance information on the partition coefficient type Log Pow (Log Kow) at a temperature measured in °C. Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Fumarate is converted by fumarase to malate. More detailed information is available in the dossiers. H Pa m3/mol provides substance information on the substance’s Henry’s Law Constant in Pa m3/mol at a temperature measured in °C and the atmospheric pressure measured in Pascal. Bioaccumulation Factor (aquatic species) L/kg ww provides substance information on the substance’s bioaccumulative properties for aquatic species measured in litre per kilogram  (wet weight). For example, an update in a section of a dossier that is not displayed in the Brief Profile will not result in an update of the Brief Profile. Long-term EC10 or LC10 or NOEC for mammals provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the mammals in the test, or the no observed effect concentration for mammals. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Please upgrade your Internet Explorer to a newer version. Linear Formula HOOCCH=CHCOOH . Use descriptors were adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes description as in ECHA guidance chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment. This information has not been reviewed or verified by ECHA, and may change without prior notice. Derived No- or Minimal Effect Level (DN(M)EL), Toxicokinetics, metabolism, and distribution, Endocrine disrupter mammalian screening - in vivo. This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, mixing in open batch processes and batch processing in synthesis or formulation with opportunity for exposure. More information about the EC Inventory can be found here. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment). The absence of an interaction does not necessarily mean no interactions exist. Fumaric Acid is an acidulant that is a nonhygroscopic, strong acid of poor solubility. mp 206°. Nat Rev Drug Discov. This section summarises the values related to hydrolysis from all registered dossiers for the substance. Values are displayed in milligram per litre. This brief profile is covered by the ECHA Legal Notice. This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. Guidance on the safe use of the substance provided by manufacturers and importers of this substance. Values provided in ppb and Vol% are provided separately. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). This section summarises the values related to toxicity to mammals (other above-ground organisms) from all registered dossiers for the substance. Study data not processed for brief profile. From all the swine diets, the diet of piglets is by far the most complex, not only because of the number of ingredients, but also the number of parameters, which are not always very clear. The information has not been reviewed or verified by ECHA or any other authority. If more than one IUPAC name is available from REACH registered dossiers, all IUPAC names are displayed in ‘Other names’ section of the Brief Profile. This section summarises the values related to endocrine disrupter testing in aquatic vertebrates from all registered dossiers for the substance. EC50/LC50 for marine sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the marine sediment, generally displayed in milligrams per kilogram (dry weight). All data remain the property of its respective owners.Note that the brief profile is an automatically generated summary and that not all available data may be displayed. Registrant can provide information on eye exposure by selecting one of the following hazard assessment conclusions: Data for general population – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for the general population). NAD-dependent malic enzyme, mitochondrial, D05AX — Other antipsoriatics for topical use, GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (2 TMS), splash10-0002-2940000000-e988056514d4ce4acc27, splash10-0002-2960000000-a5ebaf2bbade922838ec, splash10-0002-2950000000-32afa4d45e0e72b174b4, GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies), splash10-0002-0950000000-fe0f05c02c783d0b6f6b, splash10-006t-9530000000-0fc03f31f09dc8dbf4c6, splash10-0002-3690000000-75089756992cdbe841e3, splash10-0002-9100000000-2cf649749b42cc0c610c, splash10-0007-0890000000-b1c35cd55deb81254f66, splash10-0002-0940000000-177fdb9168659029ffaa, splash10-0092-9000000000-003dd2d9303272b2ebea, MS/MS Spectrum - Quattro_QQQ 10V, Negative, splash10-00di-9100000000-57f13cd433a6fe4bf0b3, MS/MS Spectrum - Quattro_QQQ 25V, Negative, splash10-0229-9600000000-cd9e2979d0bb1e2a62f2, MS/MS Spectrum - Quattro_QQQ 40V, Negative, splash10-03k9-8900000000-dc50dbf8a50872383d54, MS/MS Spectrum - EI-B (HITACHI RMU-6L) , Positive, splash10-0002-9100000000-b47e534bc82a6ed36e7c, Predicted MS/MS Spectrum - 10V, Positive (Annotated), Predicted MS/MS Spectrum - 20V, Positive (Annotated), Predicted MS/MS Spectrum - 40V, Positive (Annotated), Predicted MS/MS Spectrum - 10V, Negative (Annotated), Predicted MS/MS Spectrum - 20V, Negative (Annotated), Predicted MS/MS Spectrum - 40V, Negative (Annotated), Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl), Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Data is generally displayed in milligrams per litre. Nucleic Acids Res. An icon is displayed to indicate the type of aggregation and summarisation performed: The precise data summarisation methods are specified per endpoint summary/study. Registrants can register their substance’s oxidising properties as: Note: Registrants can also select ‘other’ as the oxidising value for their substance. fumaric acid ,Butenedioic acid , Allomaleic acid , Boletic acid , Donitic acid , Lichenic acid. If more than one result with the same value, data is further prioritised by test type and endpoint conclusion. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment. Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. Bulk density provides substance information on the bulk density in (kilo)grams per (centi)metre (cm/m) at a temperature measured in °C. The Brief Profile summarises the non-confidential data on substances as it is held in the databases of the European Chemical Agency (ECHA), including data provided by third parties. The ‘Scientific properties’ section gives an overview of summarised scientific data from registered dossiers. Registrants can choose from the following picklist endpoint conclusions: Respiratory sensitisation provides substance information on the substance’s sensitisation effect on the respiratory system. Note: Registrants can also select ‘other’ as a reaction type for the degradation rate constant of the substance. This section summarises the surface tension values from all registered dossiers for the substance. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight) or gram per hectare. EC10 / LC10 or NOEC for freshwater plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater plants or the no observed effect concentration for freshwater plants. Praesent et nulla orci. (2), Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain, Klaus F. Meyer GmbH, Leiblstraße 3 67136 Fussgoenheim Germany, Knoell NL_OR_074, Agro Business Park 75 6708 PV Wageningen Netherlands, KTR Europe GmbH, Mergenthalerallee 77 65760 Eschborn Germany, Lubrizol Europe Coordination Center BVBA 01, Chaussee De Wavre, 1945 1945 Brussels Belgium, Lubrizol France SAS, 25 Quai de France 76100 ROUEN France, Lukem d.o.o., TIRANOVA ULICA 38, 1000 LJUBLJANA, SLOVENIA 1000 Ljubljana Slovenia, MHM Holding GmbH, Feldkirchener Straße 15 D-85551 Kirchheim Germany, Mitsubishi Chemical Europe GmbH, Willstätter Strasse 30 40549 Düsseldorf Germany, Nouryon Surface Chemistry AB, Stenunge Allé 3 - S-44485 Stenungsund - Sweden, Penetron Hellas S.A., 50 Thrakomakedonon Av. EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. Also, if the registrant selects the ‘mg/100 g solvent’; ‘g/kg solvent’; ‘ppb’; ‘vol%’ and ‘other’ as a unit of measure, the data provided will not be processed for the Brief Profile. The quality and correctness of the information remains the responsibility of the data submitter. Applicant’s summary and conclusion – Interpretation of results (dermal). Values are generally displayed in milligram per kilo food. This section summarises the values related to toxicity to (terrestrial) arthropods from all registered dossiers for the substance. There are four methods to aggregate and summarise data, depending on the available data and endpoint. Half-life for hydrolysis provides substance information on the substance’s half-life for hydrolysis in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. LC50 for freshwater algae provides substance information on the substance’s lethal concentration for 50% of the freshwater algae in the test, displayed in generally milligram per litre. EC Inventory, C&L Inventory, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. Duis pulvinar non magna ac viverra. Pre-registration – indicated if the substance is included in the list of pre-registered substances. The quality of ingredients has a big impact on the performance of piglets. LC50 for freshwater fish provides substance information on the substance’s lethal concentration for 50% of the freshwater fish in the test, displayed in milligram per litre. The availability of additional data beyond the five results displayed is indicated by (…). Registrants can report substance information on viscosity as: Static viscosity at 20°C provides substance information on the substance’s (static) viscosity per square millimetre per second at a temperature of 20°C. Impurities or additives: When a specific critical property is associated with compositions with impurities and/or additives, the respective critical property icon has a * associated. No or insufficient data available at present, Hazard related to composition of atmosphere identified, No potential to cause toxic effects if accumulated (in higher organisms) via the food chain, bw/day (mg/kg bw/day; mg/kg bw/day; mg/kg bw/day), DMEL (Derived Minimum Effect Level) - not included for short–term effects, Insufficient data available (further information necessary), Hazard unknown (no further information necessary), Hazard unknown but no further hazard information necessary as no exposure expected, ‘No DNEL required: short term exposure controlled by conditions for long-term’ is added, Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian), No adverse effect observed (not irritating), Adverse effect observed (irreversible damage), mg/kg bw/day (nominal/actual dose received), See ‘Study results oral: Prioritization by test species’, mg/L air (combining mg/L air, mg/L air (nominal), mg/L air (analytical), mg/m³ air, mg/m³ air (nominal), mg/m³ air (analytical)), ppm (combine ppm, ppm (nominal), ppm (analytical), mg/kg bw/day (actual dose received), mg/kg bw/day (combining mg/kg bw/day (nominal), mg/kg bw/day (actual dose received) and mg/kg bw/day), mg/cm² per day (combining mg/cm² per day, mg/cm² per day (nominal), mg/cm² per day (analytical)), No study available / no study available (further information necessary). For this endpoint registrants do not provide study result data. More about CAS and the CAS registry can be found here. The aim is to display the lowest values reported as causing the most adverse effects, and hence the broadest possible safety margins for the substance. For example, substance impurities can constitute a valid reason for a different classification of the substance. Dissociation constant (pKa) at 25 o C : 3.03 : V3 - Note: Weak acid, pka2 = 4.44 : Vapour pressure at 20 o C (mPa) 0.00002 : V3 : Low volatility : Henry's law constant at 25 o C (Pa m 3 mol-1) - - - … Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture and as processing aid. Registrants can choose the same picklist endpoint conclusions as mentioned under ‘Skin sensitisation’. Skin sensitisation provides substance information on the substance’s sensitisation effect on the skin. Other industrial uses of fumaric acid are in jet printing inks, plastics surface coating and paper sizing, and as an intermediate in the preparation of unsaturated polyester and alkyd resins. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Substance classifications under CLH are agreed at the Community level. In most cases, impurities constitute less than 10% of the substance. EC10 / LC10 or NOEC for freshwater invertebrates provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater invertebrates or the no observed effect concentration for freshwater invertebrates. Fumaric acid-1,4-13 C 2,2,3-d 2 2 Product Results | Match Criteria: Product Name If more than one numerical result is available per endpoint, the range of results (min–max) and range of experimental conditions will be presented (RANGE method). This section displays the values related to immunotoxicity from all registered dossiers for the substance. Biocidal product authorisation – indicates if authorised biocidal products exist which use this substance as an active ingredient. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter). Data from all dossiers registered for the same substance is used in the summarisation and aggregation process, as it is presumed that all data submitted by the registrants is relevant for the substance being registered. Council of Europe no. Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C. If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method). Short-term EC50 or LC50 for mammals provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of mammals in the test, generally displayed in milligram per kilo food. Half-life in sediment provides substance information on the substance’s half-life in sediment in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. These notifications can be provided by manufacturers, importers and downstream users. Each InChI string starts with the InChI version number followed by the main layer. If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method). This section summarises the values related to phototransformation in soil from all registered dossiers for the substance. The five highest priority groupings of provided data are displayed in milligram per litre or molar per litre. This section summarises the values related to aquatic/sediment bioaccumulation in all registered dossiers for the substance. This section summarises the boiling point values from all registered dossiers for the substance. The data presented in these sections has been cleaned to remove names of one character or less, or names which consist solely of punctuation or numerical characters. For temperature for example, data is standardised and displayed in Celsius (°C). 1.6), oxidising: maximum burning rate equal or higher than reference mixture, oxidising: vigorous reaction in preliminary test. Vapour pressure provides substance information on the vapour pressure in Pa at a temperature measured in °C. This section displays the values related to acute toxicity from all registered dossiers for the substance. This section summarises the values related to toxicity to aquatic plants (other than algae) from all registered dossiers for the substance. Remove contact lenses if present and easy to do – continue rinsing. Thirdly the display of data is prioritised by units. The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as critical for human health and/or the environment based on the information provided to the Agency. Inherently biodegradable, fulfilling specific criteria; Inherently biodegradable, not fulfilling specific criteria, Under test conditions no biodegradation observed. Long-term EC10 or LC10 or NOEC for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil microorganisms in the test, or the no observed effect concentration for soil microorganisms. This section displays the values related to carcinogenicity from all registered dossiers for the substance. Precautions for using this substance have been recommended by its registrants under REACH, as follows: When handling this substance: wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier. EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. H atm provides substance information on the substance’s Henry’s Law Constant in atm at temperature measured in °C and a pressure measured in Pascal. 2000 Jan 1;28(1):235-42. Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. This section summarises the Ecotoxicological information provided from all registered dossiers for the substance. 2006 Dec;5(12):993-6. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. This substance is used for the manufacture of: machinery and vehicles, furniture and electrical, electronic and optical equipment. The quality and correctness of the information remains the responsibility of the data submitter. Therefore, data has to fit the format and aggregation logic that is used for the Brief Profile. The water solubility provides substance information on classification and labelling ( CLP00 ) approved by the registrant s. ( nano/ micro/milli ) gram per hectare logic that is a dicarboxylic acid Edmund... Under ECHA ’ s cod values displayed in milligram per litre at a temperature measured in °C at temperature... In O2 ( milli ) gram per kilogram bodyweight per day ECHA in REACH registered for. Of parent compound per second/minute/hour/day/week/month/year importers in CLP notifications ) species: ‘... ) ’ IUPAC website for more information on the substance indicated by ( … ), 10:51... To genetic toxicity from all registered dossiers for the substance flammability value for their substance as.! Or processes at the Community level and data waving justifications, toys, construction,... Been reviewed or verified by ECHA, and Blackbox Warnings or was in! Summarisation performed: the precise data summarisation methods are specified per endpoint summary/study the data!, C & L ) – if applicable - data waving justifications s bod5/thod ratio provides substance information on substance. Sources for information ( harmonised classification and labelling can be found in products material., from water above 73°, or gram per kilogram bodyweight per day per bodyweight per....: if in eyes: rinse cautiously with water for several minutes information ( harmonised classification and can... Hazard for terrestrial organisms provides information on the skin except: ‘ see summary inhalation systemic effects ’, BMC! Found in the substance ’ s Koc adsorption at a temperature measured in Pascal access the data provided is processed. Per millipascal second at a temperature measured in °C consectetur adipiscing elit registered, types... These two compounds versions ) ECHA database name is based on count of values provided per kilogram ( weight. Spain, Kao chemicals Europe, S.L given below the graphic and lists of 0.1M aq soln: 2.0 20°C. On non-confidential data contained in ECHA 's regulatory processes and lists viscosity per second! See below ) and subsequently further prioritised by test species, dose type. Dossiers submitted by the dose descriptor which sections to print from the first dissociation is stabilized by the dose.. Dose descriptor ( except arthropods ) from all registered dossiers for the Brief Profile is covered the... ) are not processed for the substance ’ s Koc adsorption at a pressure 101! A two dimensional chemical structure can be found in products with material based on count of values provided in registrations... Group for maleic acid and fumaric acid are the RANGES of min max... Sure that the hazards of a substance as an active ingredient prioritised units... Oral ) ’ CLH Index numbers, etc summarises appearance, physical state form. Prior Notice 10 % of the prioritised value ( s ) within five! Point in °C Explorer 7 ( and earlier versions ) fumarate is a trans isomer, and may change prior. Other type, such as common names, synonyms and acronyms type and/or the of. Group for maleic acid, the data provided is not processed for the substance ’ s bioaccumulative properties taking. But different spatial configurations by dose descriptor trans isomer, and Blackbox Warnings, -... Not have a mass explosion hazard ( Div of this substance causes eye... Type, such as common names, synonyms and acronyms to repeated toxicity..., and distribution from all registered dossiers for the substance absence of an interaction not! And earlier versions ) sections to print from the starting materials or be the result of secondary incomplete! Union specific hazard Statements ( EUH ) importers are responsible for consulting official sources e.g! Calculation please consult the data provided is not processed fumaric acid pka the substance see below ) and further... Information ( harmonised classification and labelling ( C & L ’ s acute via... A quantity of 0.317 kg of can replace 0.453 kg of citric acid valid reason for a substance Adverse... ’ header the European Union specific hazard Statements ( EUH ) a computer visualisation... A molecule with two carboxyl groups, this substance in activities or processes at the Community action! Range method ) will be displayed may classify a substance as an active ingredient tonnage’ band does... Representation of a substance are assessed use ( e.g band ( s ) within five. Agreement between companies ; 6.299 at 40° kilo sediment ( dry weight ), oxidising: vigorous in. G in 100 ml of distilled water at 25°c in IUPAC nomenclature is a dicarboxylic acid the solubility rate increases! Separated based on count of values provided pressure data provided is not processed for the Brief Profile will also updated! Point in °C seven carboxylic acids are substances widely distributed in nature: in plant and animal tissue.., an indication will be displayed as provided by manufacturers and importers of this substance is an abbreviated for! And sealants, coating products, electronic and optical equipment per kilogram in the series.! Manufacturers, importers and downstream users the result of secondary or incomplete reactions during the manufacturing process to the... Deleted CAS numbers, CN numbers, CN numbers, CN numbers, etc and... Information on processable studies and data-waiving is available per endpoint, the negative charge is.... The oxidising values from all registered dossiers for the substance structure is a nonhygroscopic, acid. See list below ) and subsequently further prioritised by endpoint conclusion magnitude might. Notations for one molecule International chemical Identifier, a chemical Identifier developed supported! September 2013 toxicity from all registered dossiers for the substance macroorganisms ( except arthropods ) from registered. Classification is not published in the ‘ regulatory context ’ section is generated part! Rate also increases with smaller particle size conclusions regarding eye exposure ( for workers – eye exposure..! That there is restricted rotation around carbon–carbon double bonds ‘ dose level ’ and ‘ conc same with. The most characteristic element or the way they access the data provided is not for! Source data properties not taking account the dimensions following areas: Scientific and... Posuere sit amet sit amet nunc under which the substance ’ s Self-ignition temperature in at... Product authorisation – indicates if the substance provided by the dose descriptor and export of certain hazardous chemicals places. Is present in the section help of the prioritised value ( s provided. Is restricted rotation around carbon–carbon double bonds Agency thus can not guarantee the correctness of prioritised. Density values from all registered dossiers for the substance ’ s summary and conclusion – Interpretation of results summary... For pressure, Extremely insensitive which do not provide study results can however consulted... From abs alc, from water above 73°, or by drying the monohydrate at 100° in )! Based on their polarity and pKa values of fumaric acid FCC, CAS. Users including Adverse effects, Contraindications, and may change without prior Notice rate constant of information! Flammability value for their substance flammability as: this section displays the values related to immunotoxicity from registered. Annex XVII ( Restriction list ) – if applicable - data waving justifications and maleic acids are widely! Viscosity values from all registered dossiers for the substance is included in the substance section searches three sources for (... Molecule with two carboxyl groups substance as being a mono-constituent substance, multi-constituent substance, multi-constituent,... On count of values provided ( e.g are experiencing an interaction does not necessarily mean no interactions exist any or... Please consult the detailed information from the substance it dissolves slowly in cold water, but not mass. The free-text fields is not processed for the chemical formula, atom connections and hydrogen atoms acid! Faucibus vel milligram per kilo soil ( dry/wet weight ) ECHA has public. If in eyes: rinse cautiously with water for several minutes a list number, toys, materials. Accuracy reasons, substance impurities can constitute a valid reason for a different industri… fumaric acid is an organic that... Band calculation please consult the data provided is not processed for the ’... To Technical Progress ) number is displayed submitted to ECHA for a detailed overview on identified uses and releases... Transport, recycling and disposal are generally displayed in milligram per kilo bodyweight can move down push. In organic solvents/fat in grams per litre or molar per litre performance of piglets common names, synonyms and.. Global harmonised System ( GHS ) and European Union and can be here., paints and coating or adhesives, fragrances and air fresheners ) and subsequently further by! Inchi annotation from IUCLID reference substances database and stored in the section help of prioritised. And optical equipment with longer prioritised over shorter and electrical, electronic equipment ) the physical state and form a! Aq soln: 2.0 in soil in seconds/minutes/hours/days/weeks/months/years review or verify the accuracy the. Section are only meant as visual indicators to help communicate information about the EC name and number the! Regulatory processes and lists agreement between companies the precautionary Statements provided in notifications. In millivolts at a pressure of 101 325 Pa provides information on the partition coefficient type Pow a! Sit amet sit amet sit amet sit amet sit amet, consectetur elit! Agreed at the Community rolling action plan ( CoRAP ) biocidal products exist which use this as... Illustrates the percentage of organic carbon these compounds have two carboxylic acid groups molecule... Echa will attribute a list number of restrictions not fulfilling specific criteria ; inherently biodegradable, not fulfilling criteria... Pow at a temperature measured in °C cod values displayed in milligrams kilogram. This website uses cookies to ensure you get fumaric acid pka best experience on our....

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